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Exploration of the influence of non-positive pressure ventilation on preoxygenation and the safe apnea time limit during the induction period of general anesthesia in laparoscopic surgery

Exploration of the influence of non-positive pressure ventilation on preoxygenation and the safe apnea time limit during the induction period of general anesthesia in laparoscopic surgery

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400087520
Enrollment
Unknown
Registered
2024-07-29
Start date
2024-07-29
Completion date
Unknown
Last updated
2024-08-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laparoscopic surgery for gynecological diseases

Interventions

Non-positive pressure ventilation Group A:The patient was ventilated through a closed mask. The APL valve was adjusted to set the pressure at 5 cmH2O. After 1 minute of pre-oxygenation and 8 spontaneo
Non-positive pressure ventilation Group B:The patient was ventilated through a closed mask. The APL valve was adjusted to set the pressure at 10 cmH2O. After 1 minute of pre-oxygenation and 8 spontane
Conventional ventilation Group C:The patient was ventilated through a closed mask. After 1 minute of pre-oxygenation and 8 spontaneous deep breaths, rapid sequence induction was initiated. After the l

Sponsors

Central Hospital of Shaoyang City, Hunan Province, China
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists (ASA) grades I to II; aged 18 to 65 years; normal heart, lung and liver-kidney functions; hemoglobin concentration within the normal range (Hb > 110 g/L); body mass index (BMI) = 28 kg/m2

Exclusion criteria

Exclusion criteria: Anemia (Hb 28 kg/m2

Design outcomes

Primary

MeasureTime frame
Arterial Blood Gas Analysis;

Secondary

MeasureTime frame
antrum area;

Countries

China

Contacts

Public ContactYunxi Xiao

Central Hospital of Shaoyang City, Hunan Province, China

xyx1208@163.com+86 134 6929 6765

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026