Helicobacter pylori infection
Conditions
Interventions
control group:600mg simethicone
ecperimental group:20000u Pronase
ecperimental group:600mg (N-acetylcysteine,NAC)
ecperimental group: 600mg Simethicone+ 20000u Pronase
ecperimental group: 600mg Simethicone+ 20000u Pronase+ 1g sodium bicarbonate
ecperimental group: 600mg Simethicone+ 600mg (N-acetylcysteine,NAC)
Sponsors
Zunyi Medical University Hospital
Eligibility
Sex/Gender
All
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: ?Age =40 years old, male or female; ? There is evidence of HP infection (such as positive breath test, positive serology test, positive histology test) and ME-NBI endoscopy is required.
Exclusion criteria
Exclusion criteria: (1) Diagnosed or highly suspected gastric cancer or other gastrointestinal malignancies; (2) Have a history of gastric surgery or other operations that affect gastric function; (3) Have serious heart, liver, kidney and other organ dysfunction or other serious systemic diseases; (4) There are factors that affect the clarity of gastric mucosa, such as heavy smoking, drinking, taking non-steroidal anti-inflammatory drugs, etc. (5)Have received HP eradication therapy or other antimicrobial therapy in the past month; (6)Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| visibility score; | — |
Secondary
| Measure | Time frame |
|---|---|
| ME-NBI examination time;Adverse reaction situation;Flushing frequency;Minor lesions detected;Polyp detection; | — |
Countries
China
Contacts
Public ContactJingyu Xu
Zunyi Medical University Hospital
Outcome results
None listed