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The Association of Perioperative Systemic Inflammation with Chronic Postsurgical Pain in Patients Undergoing Orthopedic Surgery

The Association of Perioperative Systemic Inflammation with Chronic Postsurgical Pain in Patients Undergoing Orthopedic Surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400087507
Enrollment
Unknown
Registered
2024-07-29
Start date
2024-08-01
Completion date
Unknown
Last updated
2024-08-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Postsurgical Pain

Interventions

Higher inflammation level group:None
Lower inflammation level group:None

Sponsors

The First Hospital of China Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: (1) Patients scheduled to undergo orthopedic surgery under general anesthesia; (2) Age >=18 years; (3) ASA grade I to II; (4) Expected postoperative hospitalization of at least 3 days.

Exclusion criteria

Exclusion criteria: (1) Patients whose medical records do not contain the data needed to assess the level of perioperative inflammation; (2) Patients with a history of drug or alcohol dependence; (3) Patients in the presence of severe pain from other causes (e.g., progressive malignancy); (4) Patients scheduled for amputation surgery; (5) Patients scheduled for postoperative ICU admission; (6) Patients scheduled for a second surgery within 60 days after the initial surgery; (7) Patients who are unable to cooperate (e.g., cognitive dysfunction, speech impairment, severe hearing or visual impairment) to complete the experiment.

Design outcomes

Primary

MeasureTime frame
Chronic Postsurgical Pain;

Secondary

MeasureTime frame
Subtype of Chronic Postsurgical Pain;Pain Disability;Acute Postsurgical Pain;

Countries

China

Contacts

Public ContactBo Fang

The First Affiliated Hospital of China Medical University

bfang@cmu.edu.cn+86 135 9165 2713

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026