thyroid cancer
Conditions
Interventions
Dexmedetomidine group:Dexmedetomidine
Control group:Normal saline
Sponsors
Fudan University Shanghai Cancer Center
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Male or female subjects aged between 18 and 65 years 2) American Society of Anesthesiologists (ASA) anesthesia grade I-III 3) Plan to receive thyroid cancer surgery 4) General anesthesia under endotracheal intubation 5) Sign the informed consent
Exclusion criteria
Exclusion criteria: 1) Patients who have undergone thyroid cancer surgery in the past 2) Patients who have been diagnosed with other malignant tumors in the past or have other malignant tumors present at the same time 3) Untreated ischemic heart disease and other severe cardiovascular diseases 4) Preoperative electrocardiogram shows the presence of heart conduction block 5) Acute or chronic respiratory failure, severe asthma, pulmonary bullae, pneumothorax, emphysema, bronchopleural fistula, etc 6) Previously diagnosed with bipolar disorder, schizophrenia, or other mental disorders 7) Cannot accept follow-up 8) Having difficulties in listening, speaking, reading, and writing 9) Allergies to dexmedetomidine, propofol, rocuronium, remifentanil, or other anesthetic ingredients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Self-Rating Anxiety Scale before surgery and on postoperative day (POD) 1, 2, and 3 after surgery;Visual analogue scale before surgery and on postoperative day (POD) 1, 2, and 3 after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative adverse reactions; | — |
Countries
China
Contacts
Public ContactZhang Jun
Fudan University Shanghai Cancer Center
Outcome results
None listed