Hypertrophic Cardiomyopathy
Conditions
Interventions
Hypertrophic cardiomyopathy patients with or without arrhythmias:None
Sponsors
Fuwai Hospital, CAMS&PUMC
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1) Patients aged 18 years and older. 2) Inpatients with a confirmed diagnosis of HCM in the cardiomyopathy department at Fuwai Hospital who consent to undergo 18F-1799 PET/CT imaging and sign the informed consent form. 3) Completion of comprehensive clinical assessments, including echocardiography, cardiac magnetic resonance imaging, functional testing, and biochemical blood tests. 4) Patients must undergo either a 24-hour Holter monitoring or a 12-lead electrocardiogram to evaluate the presence of arrhythmias based on the results.
Exclusion criteria
Exclusion criteria: 1) Patients unable to undergo PET/CT imaging. 2) Patients with a history of implanted ICD, prior surgical interventions such as Morrow surgery, alcohol septal ablation, or radiofrequency ablation aimed at relieving left ventricular outflow tract obstruction prior to enrollment. 3) Patients who have undergone arrhythmia ablation in the past. 4) Pregnant or breastfeeding women. 5) Patients with a history of myocardial infarction. 6) Patients presenting with symptoms or signs of heart failure (i.e., New York Heart Association classification III/IV, left ventricular ejection fraction [LVEF] < 50%, or other clinical evidence of heart failure).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 18F-1799 uptake intensity, left ventricular TBRmax; | — |
Countries
China
Contacts
Public ContactFang Wei
Fuwai Hospital, CAMS&PUMC
Outcome results
None listed