Exploring the effects of different anesthetic drugs on patients' respiratory function and inflammatory factors: a single center, randomized controlled trial

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400087486

Enrollment

Unknown

Registered

2024-07-29

Start date

2024-08-01

Completion date

Unknown

Last updated

2024-08-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute lung injury

Interventions

Propofol group:Anesthesia maintenance using propofol

Sevoflurane group:Anesthesia maintenance using sevoflurane

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Patients aged 18-80 undergoing general anesthesia (2) Patients scheduled for laparoscopic surgery (3) American Society of Anesthesiology (ASA) classification I-III; (4) Fasting water time = 8h; (5) Anesthesia duration 1-4 hours

Exclusion criteria

Exclusion criteria: (1) Age under 18 years old, over 80 years old (2) Proposed emergency surgery; (3) American Society of Anesthesiology (ASA) classification = Grade IV; (4) Patients with preoperative pulse oximetry below 90% (5) Preoperative pulmonary diseases such as emphysema, asthma, COPD, pneumonia, tuberculosis, lung tumors, and pleural effusion, etc

Design outcomes

Primary

Measure	Time frame
PH value;PaO2;PaCO2;SPO2;	—

Secondary

Measure	Time frame
Blood pressure;Heart rate;	—

Countries

China

Contacts

Public ContactMa ling

Shengjing Hospital of China Medical University

maling27@hotmail.com+86 189 4025 6927

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026