Pain
Conditions
Interventions
liposomal bupivacaine group:Bilateral lateral transversus abdominis plane block by an anesthesiologist under ultrasound guidance with liposomal bupivacaine 266 mg, diluted by normal saline into 40 ml,
normal saline group:Bilateral lateral transversus abdominis plane block by an anesthesiologist under ultrasound guidance with 20 ml normal saline in each side, and together with the multimodal analges
Sponsors
International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: Patients with the age of 20-40, American Society of Anesthesiologist II, singletons with 37-42 gestional weeks, undergoing elective cesarean delivery and request for post operative analgesia.
Exclusion criteria
Exclusion criteria: Contraindications to epidural and spinal anesthesia, coagulation disorders, allergy to anesthetics (including liposomal bupivacaine, ropivacaine, hydromorphone, oxycodone and acetaminophen), severe stomach upset or stomach diseases, body mass index over 32 kg/m2, history of drug abuse and patient refusal.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Consumption of oxycodone; | — |
Secondary
| Measure | Time frame |
|---|---|
| Numeric rating scale scores of resting, turning over, walking and uterus contraction;QoR-15 scores;Edinburgh scores;satisfaction scores; | — |
Countries
China
Contacts
Public ContactTao Xu
International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University
Outcome results
None listed