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Effect of point-of-care PCR on antibiotic prescribing in children with community-acquired pneumonia in outpatient settings: A randomized, controlled, non-inferiority study

Effect of point-of-care PCR on antibiotic prescribing in children with community-acquired pneumonia in outpatient settings: A randomized, controlled, non-inferiority study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400087470
Enrollment
Unknown
Registered
2024-07-29
Start date
2024-08-01
Completion date
Unknown
Last updated
2024-08-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Community-acquired pneumonia

Interventions

Intervention Group:point-of-care PCR
Control Group:none

Sponsors

Beijing Children's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 18 Years

Inclusion criteria

Inclusion criteria: ? Community-onset; ? Pneumonia-related clinical manifestations: 1) newly developed cough, sputum, or worsening of existing respiratory disease symptoms, with or without purulent sputum, chest pain, dyspnea, and hemoptysis; 2) fever; 3) signs of pulmonary consolidation and/or moist rales; 4) chest imaging examination showing new patchy infiltration shadows, lobar or segmental consolidation shadows, ground-glass shadows, or interstitial changes, with or without pleural effusion; 5) pneumonia initially diagnosed at Beijing Children's Hospital; 6) complete clinical information.

Exclusion criteria

Exclusion criteria: ? Patients suspected or confirmed of bacterial infection in other parts of the body (urinary tract infection, skin and soft tissue infection, osteomyelitis, bloodstream infection, etc.);? Patients with incomplete clinical data.

Design outcomes

Primary

MeasureTime frame
Antibiotic prescription rate;

Secondary

MeasureTime frame
time to resolution of fever;Antibiotic use (DOTs, types);clinical outcome;

Countries

China

Contacts

Public ContactChen Tianming/Li Yuchuan

Beijing Children's Hospital

chentianming1983@aliyun.com+86 10 5960 6311

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026