postoperative nausea and vomiting
Conditions
Interventions
Control group:None
Noise Reduction group:Wearing noise-cancelling headphones (3MTM PeltorTM X5A acoustic noise-cancelling earmuffs)
Sponsors
The First Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Female patients aged 18-65 years; 2) ASA physical status I to II; 3) Laparoscopic gynaecological surgery under general anaesthesia with an estimated operative time more than 30 minutes;
Exclusion criteria
Exclusion criteria: 1) Pregnant and breastfeeding patients; 2) History of cancer chemotherapy; 3) Average thresholds >40 dB at four frequency points: 500, 1000, 2000, 4000, 6000, 8000 Hz on pure tone audiometry (PTA); 4) Comorbidities known to increase the risk of PONV: e.g. impaired gastric motility and vestibular disease; 5) Liver or renal dysfunction (ChildPugh class C or renal replacement therapy); 6) Long-term history of sedative, antidepressant or psychoactive drug abuse, history of alcoholism, etc; 7) History of central nervous system disease, psychiatric disease or speech communication disorder; 8) Using antiemetic and psychotropic drugs or glucocorticoids within 24 hours before surgery; 9) Unable to wear headphones due to auricular deformity or other reasons; 10) Hypersensitivity to study medication.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence of postoperative nausea and vomiting (PONV); | — |
Secondary
| Measure | Time frame |
|---|---|
| the severity of PONV;antiemetic rescue therapy;pain scores at rest and while coughing;need for rescue analgesia;Quality of postoperative recovery;Postoperative sleep quality;adverse effects related to anesthetics (hypertension, hypotension, tachycardia, bradycardia, postextubation low oxygen saturation, chills, awakening agitation, excessive sedation, severe arrhythmia, cardiac arrest, hypothermia);length of PACU stay;time to extubation;length of postoperative hospital stay; patient satisfaction;a composite variable of major Major postoperative complications; | — |
Countries
China
Contacts
Public ContactLiu Huayue
The First Affiliated Hospital of Soochow University
Outcome results
None listed