osteoporosis
Conditions
Interventions
teriparatide alone group:None
combined calcium supplements group:None
combined active vitamin D group:None
combined calcium supplements and active vitamin D group:None
Sponsors
Shanghai Sixth People's Hospital
Eligibility
Sex/Gender
All
Age
45 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1.Postmenopausal osteoporotic women with =1 year of menopause 2. Bone mineral density T-value <-3.0 in the lumbar spine, femoral neck, or total hip; or at least one osteoporotic fracture after menopause 3.Treatment with teriparatide 4. Available pre-dose biochemical test results and followed up at least once at 3 months, 6 months, or 1 year post-dose.
Exclusion criteria
Exclusion criteria: 1. Intravenous bisphosphonates within 1 year 2. Use of desutumumab within 6 months 3. Have other metabolic bone disease (e.g. osteochondrosis, osteogenesis imperfecta, Paget's disease) 4. Unwilling to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| serum calcium; | — |
Secondary
| Measure | Time frame |
|---|---|
| bone density;Serum procollagen type I N-terminal propeptide;Serum osteocalcin;Serum type ? collagen C-terminal peptide crosslinking; | — |
Countries
China
Contacts
Public ContactYue Hua
Shanghai Sixth People's Hospital
Outcome results
None listed