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Cerebral response of stroke patients and matched control subjects to a somatosensory stimulation with XNKQ acupuncture compared to control interventions measured with fMRI

Cerebral response of stroke patients and matched control subjects to a somatosensory stimulation with XNKQ acupuncture compared to control interventions measured with fMRI

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400087420
Enrollment
Unknown
Registered
2024-07-26
Start date
2023-04-14
Completion date
Unknown
Last updated
2024-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

Stroke patient group:Receive acupuncture treatment for awakening the brain and opening the orifices or control acupuncture treatment in random order
Healthy subject group:Receive acupuncture treatment for awakening the brain and opening the orifices or control acupuncture treatment in random order

Sponsors

First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria of stroke group: a. 35-70 years old, right-handed; b. Brain infarction was diagnosed by CT or MRI as a dead person, the first onset, right basal ganglia infarction, accompanied by left motor dysfunction, the onset of 2 weeks to 6 months, the condition is basically stable, unconsciousness and obvious language disorders; c. No previous family genetic history of mental and nervous system; d. Have not taken any excitatory drugs in recent 2 months; e. Sign the informed consent form. Inclusion criteria of control group (healthy brain): a. Age matched with sex and stroke group, right handed; b. The brain is healthy after CT or MRI examination, which may be accompanied by diseases of other systems of the body except cerebrovascular diseases, such as heart disease, digestive system diseases, etc; c. No previous family genetic history of mental and nervous system; d. Have not taken any excitatory drugs in recent 2 months; e. Sign informed consent

Exclusion criteria

Exclusion criteria: Exclusion criteria of stroke group: a. Cerebrovascular disease is in progress or vital signs are unstable; b. Patients with aphasia, severe dementia, psychosis or post-stroke depression; c. Have a history of other neurological diseases, such as multiple sclerosis (MS); d. Severe heart, lung, liver and kidney function injury; e. There is metal in the body, after the heart is installed with pacemaker, stent and bypass surgery, claustrophobia or other people who cannot be examined by magnetic resonance imaging; f. Intolerant of acupuncture; g. Pregnant and lactating women; h. Currently, he is participating in other clinical researchers. Exclusion criteria of control group (healthy brain): a. Unstable vital signs; b. Have a history of nervous system diseases; c. Patients with aphasia, severe dementia and psychosis; d. Severe heart, lung, liver and kidney function injury; e. There is metal in the body, after the heart is installed with pacemaker, stent and bypass surgery, claustrophobia or other people who cannot be examined by magnetic resonance imaging; f. Intolerant of acupuncture; g. Pregnant and lactating women; h. Currently, he is participating in other clinical researchers.

Design outcomes

Primary

MeasureTime frame
fMRI;

Countries

China

Contacts

Public ContactChang Yinghui

First Teaching Hospital of Tianjin University of Traditional Chinese Medicine

byh_beilei@163.com+86 158 2272 3977

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026