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Clinical study on oral administration of Sanyi Le active lactic acid bacteria powder to improve abnormal lipid metabolism in PCOS patients: a multicenter prospective clinical cohort study

Clinical study on oral administration of Sanyi Le active lactic acid bacteria powder to improve abnormal lipid metabolism in PCOS patients: a multicenter prospective clinical cohort study

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400087399
Enrollment
Unknown
Registered
2024-07-26
Start date
2024-08-01
Completion date
Unknown
Last updated
2024-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic ovary syndrome

Interventions

Intervention group:Oral Shanyile active lactic acid bacteria powder for 8 weeks, 2 bags per day (i.e. 4g)

Sponsors

Zhejiang Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: (1) Women diagnosed with PCOS according to Rotterdam standards; (2) 20 to 40 years old; (3) BMI >=25 and/or disordered lipid metabolism index (two consecutive fasting tests for cholesterol or triglycerides above the upper limit)

Exclusion criteria

Exclusion criteria: (1) Patients with organic obesity (such as hypothyroidism, Cushing syndrome, etc.); (2) abnormal liver and kidney function; (3) patients with chronic malabsorption syndrome or chole depression; (4) oral metformin, olistar, GLP-1 agonists and other drugs within one month before joining the group to lose weight or improve glycolipid metabolism; (5) Those who take antibiotics or other probiotics within two weeks before joining the group; (6) A history of estrogen or metabolic drug treatment in the past month

Design outcomes

Primary

MeasureTime frame
Blood fat;Body mass index;Waistline;Hip measurement;Body fat distribution;

Secondary

MeasureTime frame
Fasting blood sugar;2h blood sugar;Fasting insulin;2h insulin;sex hormone;Thyroid function;Anti-Mueller tube hormone (AMH);Number of antral follicles;The size of the ovary;ntestinal flora;Vaginal flora;

Countries

China

Contacts

Public ContactXiaohua Fu

Zhejiang Provincial People's Hospital

Fxh9210@163.com+86 138 5806 0150

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026