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Comparative intervention study on the efficacy and safety of pyloroplasty and pyloric dilation in preventing postoperative reflux esophagitis in proximal gastric cancer patients

Comparative intervention study on the efficacy and safety of pyloroplasty and pyloric dilation in preventing postoperative reflux esophagitis in proximal gastric cancer patients

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400087396
Enrollment
Unknown
Registered
2024-07-26
Start date
2024-08-01
Completion date
Unknown
Last updated
2024-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastroesophageal reflux disease

Interventions

Pyloriplasty group:Pyloriplasty
Pyloric Dilation Surgery Group:Pyloric Dilation Surgery
control group:None

Sponsors

Northern Jiangsu People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1: Age range from 18 to 70 years old, regardless of gender 2: Confirmed as gastric cancer by histopathology and requiring surgical treatment 3: Patients who plan to undergo proximal gastrectomy after preoperative evaluation 4: Voluntarily participate in the study and agree to cooperate with the researcher in data collection

Exclusion criteria

Exclusion criteria: 1: Subjects who died during hospitalization or were automatically discharged and terminated treatment 2: Subjects who require total gastrectomy during surgery 3: Subjects with severe coagulation abnormalities 4: Late stage tumor subjects who have been confirmed to have unresectable tumors invading surrounding organs or distant metastases only meet the criteria for palliative resection 5: Pregnant and lactating women 6: Subjects undergoing emergency surgery due to bleeding, perforation, and intestinal obstruction 7: Combined severe infection 8: Subjects with severe heart or lung disease 9: Subjects who are unable to cooperate with this study due to psychological, family, or social reasons and refuse to sign informed consent forms

Design outcomes

Primary

MeasureTime frame
Lower esophageal pH value;

Countries

China

Contacts

Public ContactDong Tang

Subei People's Hospital

83392785@qq.com+86 189 5278 3556

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026