Postoperative delirium
Conditions
Interventions
Active-tACS :The Active-tACS group was given a 60min 2mA 40Hz tACS treatment once. The stimulation site was: the stimulation electrode was located in the left dorsolateral prefrontal cortex, and the c
Sham-tACS:The results were the same as those of true stimulation group except that there was no current after 40s of stimulation.
Sponsors
Yantai Affiliated Hospital of Binzhou Medical University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Elderly patients aged 65 years old over who speak Chinese; 2. The expected hospital stay is more than 3 days; 3. ASA grade is II ~ III; 4. Intravenous and inhalation combined anesthesia + peripheral nerve block; 5. Patients or family members sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Have a neuropsychiatric disorder or a history of previous neuropsychiatric or psychiatric disorders, and a simple mental status examination score (MMSE) < 15 points; 2. Craniocerebral or scalp injury; 3. Patients with a history of serious cardiovascular disease, severe liver or kidney dysfunction; 4. There are metal implants in the body; 5. Drug or alcohol abuse, visual or hearing impairment, communication impairment; 6. Patients who are expected to need intubation after surgery and thus cannot undergo cognitive assessment; 7. Patients who are allergic to benzodiazepines or have contraindications; 8. Patients who have participated in other drug trials within 1 month before the planned surgery; 9. Patients with hemoglobin < 90g/L; 10. Refusing to sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain;Sleep;Postoperative anxiety and depression;Postoperative quality of recovery score; | — |
Countries
China
Contacts
Public ContactJia Shushan
Yantai Affiliated Hospital of Binzhou Medical University
Outcome results
None listed