Alzheimer's disease
Conditions
Interventions
Electroacupuncture group:Electroacupuncture
Electroacupuncture+Repetitive transcranial magnetic stimulation group:Electroacupuncture+Repetitive transcranial magnetic stimulation
Sponsors
Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
50 Years to 85 Years
Inclusion criteria
Inclusion criteria: (1) Comply with the NIA-AA standard and the most likely AD standard; (2) 50 years old= age = 85 years old; (3) 0.5 points= clinical dementia rating score =2 points; (4) Sign the informed consent form and voluntarily participate in this trial; If the subject has the ability to make a decision, he or she will sign the informed consent form; If the patient's cognitive level is low and he or she is unable to sign the informed consent, the legal guardian will sign it on his/her behalf.
Exclusion criteria
Exclusion criteria: (1) Accompanied by other neurological diseases or non-neurological diseases that can cause cognitive dysfunction or progressive memory impairment; (2) There are contraindications to acupuncture treatment, such as bleeding tendency at acupuncture points or allergy to metals; (3) Implantation of pacemakers, cochlear implants and defibrillators, etc.; (4) Severe magnetic allergic reaction; (5) Craniotomy or history of seizures; (6) there were no relatively fixed caregivers during the 16-week study period; (7) Participating in other clinical trials at the time of enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Alzheimer disease assessment scale cognition, ADAS-Cog; | — |
Secondary
| Measure | Time frame |
|---|---|
| Neuropsychiatric Inventory, NPI;Neuropsychiatric Inventory, NPI;Pittsburgh sleep quality index, PSQI;Clinician Interview–Based Impression of Change scale, CIBIC; | — |
Countries
China
Contacts
Public ContactBaohui Jia
Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Outcome results
None listed