A clinical study of the effects of blood flow restriction combined with aerobic training on the rehabilitation of stroke-related sarcopenia based on the ICF framework

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400087378

Enrollment

Unknown

Registered

2024-07-25

Start date

2023-12-01

Completion date

Unknown

Last updated

2024-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

Low Intensity Interval Aerobic Group (LI):A cycling program with 40% VO2max load.

Low-intensity intermittent aerobic combined with blood flow restriction group (LIBFRT):The LIBFRT group, on top of the LI Group, a 10-cm compression cuff was used to apply pressure in the middle of th

High Intensity Interval Aerobic Group(HI):The HI Group was based on the LI Group, and the cycling resistance load was set to 80% VO2max.

Eligibility

Sex/Gender

All

Age

60 Years to No maximum

Inclusion criteria

Inclusion criteria: ? Age =60 years; ? Meet the diagnostic criteria of the China Acute Ischemic Stroke Diagnosis and Treatment Guidelines 2018, and has been confirmed by head CT or MRI to have a new unilateral cerebral infarction lesion; First onset of illness; Vital signs are stable and there are no conscious disturbances; ? Meet the diagnostic criteria of "Asian Myasthenia Gravis Working Group Guidelines 2019"; ? Combined unilateral hemiparesis, Brunnstrom stage = III, modified Ashworth grade < II; muscle strength = III; (v) Duration of the disease < 3 months and no aggravation of the disease in the last month; (vi) Informed consent of the patients and their family members, and signing of the informed consent form.

Exclusion criteria

Exclusion criteria: ? People with a history of mental or cognitive disorders; ? Combined arthritis, joint injury, severe osteoporosis or fracture and other diseases that affect motor function; ? History of venous thrombosis or coagulation disorders; ? Combined cardiovascular diseases (heart failure, unstable angina, aortic stenosis, arrhythmia, hypertrophic cardiomyopathy, ST-segment depression); ? Pacemaker or other metal inserts in the body; (6) Inability to tolerate rehabilitation training due to serious basic diseases, functional disorders, systemic infections and malignant tumors.

Design outcomes

Primary

Measure	Time frame
Cortical hemoglobin concentration;	—

Secondary

Measure	Time frame
Peak moments of knee extensors;rectus femoris muscle cross-sectional area;Fugl-Meyer Motor Function Rating Scale;Minimum Mental State Examination;36-item short from health survey, SF-36;	—

Countries

China

Contacts

Public Contactzhu yonggang

Lianyungang First People's Hospital

lygzhuyg@163.com+86 518 6132 5963

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026