Depression, anxiety
Conditions
Interventions
Group A:Induction of maintenance and analgesia using esketamine and dexmedetomidine
Group B:Inducing maintenance and analgesia using propofol and sufentanil
Sponsors
Huai'an First Hospital Affiliated to Nanjing Medical University
Eligibility
Sex/Gender
All
Age
27 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing thoracoscopic lung surgery on a scheduled date 2. ASA classification: Level I-III. 3. Age range from 18 to 65 years old, BMI = 30kg/m2, junior high school education or above. 4. Those who have been approved by the hospital ethics committee to sign a written consent form to participate in this study.
Exclusion criteria
Exclusion criteria: 1. Patients with severe heart, liver, and kidney dysfunction: heart failure, myocardial infarction, left ventricular ejection fraction<30%, Child Pugh C-grade, renal dialysis. 2. History of previous lung surgery. 3. Patients with a history of allergy to anesthetic drugs or contraindications for the use of ketamine, dexmedetomidine, and nonsteroidal anti-inflammatory drugs. 4. If there is a mental disorder, a neuropsychiatric scale was used for screening before surgery. 5. Addiction or dependence on opioid and hypnotic drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Self-rating depression scale scores;Self-rating Anxiety scale scores;Numeric Rating Scale pain score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sleep Quality Numeric Rating Scale ; | — |
Countries
China
Contacts
Public ContactLi guangming
The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University
Outcome results
None listed