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Construction of differentiation criteria for coronary heart disease based on the innovative pathogenesis of "Phlegm and Stasis Transforming into Toxic Pathogen" and multi-omics pathogenesis interpretation

Construction of differentiation criteria for coronary heart disease based on the innovative pathogenesis of "Phlegm and Stasis Transforming into Toxic Pathogen" and multi-omics pathogenesis interpretation

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400087368
Enrollment
Unknown
Registered
2024-07-25
Start date
2024-07-29
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary heart disease

Interventions

Control Group:None
High levels of hsCRP in coronary heart disease:None
Low levels of hsCRP in coronary heart disease:None

Sponsors

Shenzhen Hospital of Integrated Traditional Chinese and Western Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1) Patient: meets the diagnostic criteria for unstable angina pectoris; 2) Control population: those who do not meet the diagnostic criteria for coronary heart disease; 3) Age = 18, agree to participate in this study.

Exclusion criteria

Exclusion criteria: 1) Severe liver and kidney dysfunction; 2) Malignant tumors or autoimmune diseases; 3) Acute and chronic infectious diseases, or major surgery, trauma and use of antibiotics/immunosuppressants in recent 2 weeks; 4) Merge with other serious heart diseases, such as viral myocarditis, severe valve stenosis, etc; 5) Other situations that researchers consider unsuitable for participation in the study, such as pregnancy.

Design outcomes

Primary

MeasureTime frame
hsCRP;Untargeted metabolomics;Proteomics;Targeted protein validation;

Secondary

MeasureTime frame
Blood routine;Blood biochemical index;Blood lipids ;Traditional Chinese Medicine Symptoms;Traditional Chinese Medicine Syndrome;

Countries

China

Contacts

Public ContactFANG Hong-cheng

Shenzhen Hospital of Integrated Traditional Chinese and Western Medicine

421590542@qq.com+86 136 0256 8079

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026