Nausea and vomiting
Conditions
Interventions
Q group (Quick infusion group) :Group Q (Quick infusion group) : At the beginning of closing the joint capsule, 100ml tranexamic acid with concentration of 5mg/ml (divided into two 50ml syringes at th
Group L (Slow infusion group):Group L (slow infusion group) : 100ml tranexamic acid at a concentration of 5mg/ml (divided into two 50ml syringes and injected intravenously at a speed of 100ml/h at the
Sponsors
Ningxia Hui Autonomous Region People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) Patients with age > 18 years and ASA grade I-III; (2) Patients undergoing total knee arthroplasty under lumbar anesthesia; (3) Patients who have passed the review of ethics committee and signed informed consent
Exclusion criteria
Exclusion criteria: (1) Patients with a history of serious cardiovascular and cerebrovascular diseases; (2) Patients with history of deep vein thrombosis or pulmonary embolism; (3) Patients with abnormal coagulation or renal function; (4) Refusal of intraspinal anesthesia or contraindications; (5) Patients who refused to participate in this study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of nausea and vomiting ; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of nausea and vomiting ;Hemoglobin level;Hematocrit level;Use of therapeutic antiemetic drugs; | — |
Countries
China
Contacts
Public ContactQingshan Ye; Yuhua Zou
Ningxia Hui Autonomous Region People's Hospital
Outcome results
None listed