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The efficacy and safety of fractional ablative carbon dioxide laser for periorbital wrinkles in Chinese population

The efficacy and safety of fractional ablative carbon dioxide laser for periorbital wrinkles in Chinese population

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400087320
Enrollment
Unknown
Registered
2024-07-25
Start date
2022-11-10
Completion date
Unknown
Last updated
2024-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

static wrinkles

Interventions

Group A:CO2 AFL 15-20mj, 5%
Group B:CO2 AFL 10-12.5mj, 15%
Group C:CO2 AFL 12.5-15mj, 10%

Sponsors

Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients present with static periorbital wrinkles, 25-65 years old, male or female; 2. never received other treatments for periorbital wrinkles, 3. agree for self-controlled trials and follow-up.

Exclusion criteria

Exclusion criteria: 1. Pregnant women or women planning to conceive; 2. Allergic to surface anesthetics; 3. Patients with wounds around the eyes or skin ulcers; 4. Patients with severe organic or mental illness; 5. Patients participating in other clinical trials.

Design outcomes

Primary

MeasureTime frame
Fitzpatrick wrinkles scale;

Secondary

MeasureTime frame
VISIA analysis;GAIS evaluation;

Countries

China

Contacts

Public ContactLin Xiaoxi

Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine

linxiaoxi@126.com+86 137 0199 7136

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 5, 2026