Atopic Dermatitis
Conditions
Interventions
the intervention group:basic treatment+topical glycyrrhizin cream
the control group:basic treatment+topical desonide cream
Sponsors
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Meets the diagnostic criteria for atopic dermatitis according to both Western and traditional Chinese medicine standards; 2.Disease severity is classified as mild to moderate (i.e., Investigator’s Global Assessment (IGA) score of 2-3 or Eczema Area and Severity Index (EASI) score of 1-21); 3.Age between 18 and 70 years, inclusive, with no gender restriction; 4.Understands, agrees to participate in the study, and signs the informed consent form.
Exclusion criteria
Exclusion criteria: Individuals with other active skin diseases that may affect the assessment of the condition; Individuals who have received systemic treatment with investigational drugs, biologics, or immunosuppressants within the past month; Individuals experiencing severe, uncontrollable local or systemic acute or chronic infections; Individuals with severe systemic diseases, or those with clinical test results falling into any of the following categories: alanine aminotransferase (ALT) or aspartate aminotransferase (AST) levels greater than 1.5 times the upper limit of normal; creatinine levels greater than 1.5 times the upper limit of normal; any of the main blood routine parameters (white blood cell count, red blood cell count, hemoglobin, platelet count) below the lower limit of normal; or other laboratory abnormalities deemed by the investigator to be unsuitable for participation in the study; Individuals with a history of malignant tumors, primary or secondary immunodeficiency, hypersensitivity, or a family history of tumors; Individuals who have undergone major surgery within the past 8 weeks or will need such surgery during the study period; Pregnant or breastfeeding women; Individuals with a history of alcohol abuse, drug abuse, or substance misuse; Individuals with a serious psychiatric history or a family history of psychiatric disorders; Individuals deemed unsuitable for participation in this study by the investigator for other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Eczema area and severity index, EASI; | — |
Secondary
| Measure | Time frame |
|---|---|
| Dermatology Life Quality Index, DLQI;IGA;VAS; | — |
Countries
China
Contacts
Public ContactBin Li
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200437, China
Outcome results
None listed