The effect of transnasal humidified rapid-insufflation ventilator exchange versus facemask on safe apnoea time in elderly patients with spinal cord injury

Application of apneic oxygenation technology in clinical anesthesia

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400087279

Enrollment

Unknown

Registered

2024-07-24

Start date

2024-07-29

Completion date

Unknown

Last updated

2024-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

spinal cord injury

Interventions

THRIVE group:Applying the transnasal humidified rapid insufflation ventilatory exchange (THRIVE) technique for preoxygenation and maintaining oxygenation during apnea.

facemask group:Applying mask ventilation for preoxygenation and maintaining oxygenation during apnea.

Eligibility

Sex/Gender

All

Age

60 Years to No maximum

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists physical status (ASA <=2), aged 60 years or older, Body Mass Index (BMI) between 19 and 25 kg/m2 spinal cord injury

Exclusion criteria

Exclusion criteria: History of allergy to anesthetic drugs Anticipated difficult airway preoperatively Upper airway obstruction (foreign body in the airway, snoring, etc.) Abnormalities of the nasopharynx (sinusitis, turbinate hypertrophy, deviated nasal septum, nasopharyngeal carcinoma, etc.) Other diseases affecting normal ventilation Skull base fracture or suspicion thereof Gastroesophageal reflux, high gastric pressure

Design outcomes

Primary

Measure	Time frame
safe apnoea time;	—

Secondary

Measure	Time frame
antral area;	—

Countries

China

Contacts

Public ContactGang Wu; Zhenguo Luo

Xi'an Honghui Hospital

youzhen.li@qq.com+86 135 1918 5616

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026