Atopic dermatitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: a. Meet the Williams diagnostic criteria for atopic dermatitis; b. Any gender, age 18-55 years old; c. The target lesion is 2-10 cm in diameter, located on the limbs or trunk; d. Mild atopic dermatitis with eczema area and severity index (EASI)=6 points; e. Lesion area < 5% body surface area before treatment (assessed according to the palm method, 1% based on the patient's palm area); f. Sign informed consent, voluntarily participate in this project, and insist on regular follow-up as required.
Exclusion criteria
Exclusion criteria: a. Pregnant or lactating women; b. Received AD systemic therapy within three months and local therapy or phototherapy within the last two weeks; c. Have serious heart, lung, gastrointestinal, liver, kidney and other systemic diseases or mental diseases; d. Allergic to calcium preparations; e. Have a systemic or active skin disease (e.g., psoriasis) that may affect the evaluation of the test results; f. Patients with scars, birthmarks, tattoos, sun spots, etc. in the affected area that may affect the evaluation of skin lesions; g. Patients with bacterial, viral or fungal infections requiring anti-infective therapy; h. Patients who have participated in or are participating in a clinical study of another investigational drug within one month; i. Investigators with communication barriers who could not complete the questionnaire independently.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effective after 2 weeks of treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Eczema Area and Severity Index (EASI) score;Therapeutic effectiveness;Visual analogue scale (VAS);The investigator's global assessment (IGA);Dermatology life quality index (DLQI);Take pictures of the affected area; | — |
Countries
China
Contacts
Shanghai Dermatology Hospital