sepsis acute lung injury, SALI
Conditions
Interventions
Compound Folly Capsule Group:Oral Compound Poria capsules combined with conventional treatment
Placebo group:Oral placebo plus usual care
Sponsors
The Affiliated Hospital of Hunan Academy of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: ? Age between 18 and 80; ? Meets the diagnostic criteria for sepsis (as defined by the Sepsis 3.0 guidelines from the Surviving Sepsis Campaign); ? Meets the diagnostic criteria for acute lung injury (as defined by the Berlin definition); ? Diagnosis by both traditional Chinese and Western medicine agreed upon by two guiding experts from the research team; ? The patient or family is informed and voluntarily signs the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Incomplete records of laboratory examination and disease course information; (2) pregnant or lactating women; (3) Patients with other serious physical diseases, AIDS, malignant tumors and mental illness; (4) patients who receive only hospice care; (5) Congenital or acquired immunodeficiency; (6) Those who are participating in clinical trials of other drugs, and those who are known to be allergic to therapeutic drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 28-day mortality;90-day mortality;Comprehensive efficacy of the disease;TCM syndrome efficacy;Indicators of acute lung injury;Incidence of ARDS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Venous blood markers;Arterial blood gas analysis;Indicators of organ dysfunction;Economic evaluation indicators;Indicators of immune function;Stool indicators;Lung imaging indicators; | — |
Countries
China
Contacts
Public ContactHuang Ren
The Affiliated Hospital of Hunan Academy of Traditional Chinese Medicine
Outcome results
None listed