Subclinical depression and mild cognitive impairment (MCI)
Conditions
Interventions
Subclinical Depression Group:Digital mindfulness combined with music-exercises-cognitive activity (MECA)
MCI group:Digital cognitive training
Sponsors
Peking University Sixth Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 85 Years
Inclusion criteria
Inclusion criteria: Subclinical Depression Group: Age = 60 years; both genders; right-handed; education level of primary school or above; score on the Geriatric Depression Inventory (GDI) = 2 points (0-12 points), not meeting the diagnostic criteria for major depressive disorder. MCI Group: Age = 60 years; both genders; right-handed; education level of primary school or above; meeting the diagnostic criteria for Mild Cognitive Impairment (MCI) proposed by Petersen et al.; self-reported cognitive decline confirmed by an informant; Montreal Cognitive Assessment (MoCA) score = 26 points, Activities of Daily Living (ADL) score = 20 points, not meeting the criteria for dementia diagnosis.
Exclusion criteria
Exclusion criteria: Exclusion criteria for the Subclinical Depression Group: history of schizophrenia, bipolar affective disorder, other mental disorders such as substance abuse, or alcohol abuse; dementia due to various causes; current severe physical or neurological diseases. Exclusion criteria for the MCI Group: dementia due to various causes; definite cerebrovascular diseases (including cerebral hemorrhage, cerebral infarction); other systemic or brain diseases that can cause cognitive decline; history of mental disorders such as schizophrenia, affective disorders; history of substance abuse or alcohol abuse; history of severe head trauma.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Response rate;Accomplishment ratio; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cognition;Emotion;Function; | — |
Countries
China
Contacts
Public ContactTao Li
Peking University Sixth Hospital
Outcome results
None listed