Microvascular angina
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Meet the diagnostic criteria of microvascular angina; 2) Age 18-79 years old; 3) TCM syndrome differentiation is consistent with qi stagnation and phlegm obstruction and blood stasis pattern; 4) Have not taken Chinese medicine within 1 week; 5) Signed informed consent.
Exclusion criteria
Exclusion criteria: 1) Patients with one of the following diseases: ST elevation changes on ECG, or coronary spasm on coronary angiography; After PCI, after coronary artery bypass, old myocardial infarction; myocardial bridge; Degree II. type II or above sinus or atrioventricular block with no pacemaker implanted, difficult-to-control malignant arrhythmia; dilated cardiomyopathy, hypertrophic obstructive cardiomyopathy, myocarditis, pulmonary embolism, severe valvular disease, cor pulmonale; 2) Patients with non-cardiogenic chest pain caused by pleura, gastrointestinal tract, intercostal neuralgia and other diseases; 3) Patients with endocrine diseases such as diabetes mellitus and hyperthyroidism, severe anemia (hemoglobin =9g/dl), and other diseases that affect survival (such as malignant tumors); 4) Patients with abnormal liver and kidney function (alanine aminotransferase, aspartate aminotransferase or serum creatinine is more than 2 times higher than the upper limit of normal); 5) Those who are allergic to the test drug; 6) Those who have participated in other drug clinical studies in the past 2 months; 7) Women who are pregnant, planning to become pregnant, or breastfeeding; 8) Those who are considered inappropriate by the investigators to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Peak oxygen consumption;Seattle Angina Questionnaire (SAQ) Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cardiopulmonary exercise test: oxygen uptake (VO2), metabolic equivalent, O2 Pulse, Exercise load (watt), Exercise time, Hate rate, etc;Syndrome scoring table of Traditional Chinese Medicine; | — |
Countries
China
Contacts
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine