Atrial fibrillation
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients with atrial fibrillation :(1) aged 18-80 years; (2) Patients have certain language expression and understanding ability, understand and voluntarily fill in the informed consent form, cooperate with the completion of blood testing, stool collection and scale filling (PHQ-9); (3) Previous electrocardiogram or holter electrocardiogram or portable electrocardiograph indicated atrial fibrillation; (4) Patients with paroxysmal and persistent atrial fibrillation were included. Type definition of atrial fibrillation: paroxysmal atrial fibrillation refers to spontaneous termination within 7 days of onset or intervention termination of atrial fibrillation, persistent atrial fibrillation refers to a duration of more than 7 days of atrial fibrillation, including > Prolonged atrial fibrillation refers to a type of atrial fibrillation that has lasted for more than 12 months when rhythm control strategies are decided upon. Permanent atrial fibrillation refers to a type of atrial fibrillation in which the doctor and the patient jointly decide not to restore or maintain sinus rhythm, reflecting the attitude of the patient and the doctor towards the treatment of atrial fibrillation, rather than the pathophysiological characteristics of atrial fibrillation itself. If rhythm control is reconsidered, long-term persistent atrial fibrillation is treated. Healthy Group: (1) Age 18-80 years old, gender unlimited; (2) Patients have certain language expression and understanding ability, understand and voluntarily fill in the informed consent form, cooperate with the completion of blood testing, stool collection and scale filling (PHQ-9); (3) There was no history of atrial fibrillation, and previous ECG or holter ECG showed sinus rhythm.
Exclusion criteria
Exclusion criteria: (1) Patients with a history of ablation of atrial fibrillation, valvular atrial fibrillation, severe organic heart disease, acute phase of infection, autoimmune disease, severe hepatic and renal insufficiency, pregnancy, or mental abnormality; (2) Patients with transient atrial fibrillation secondary to reversible causes: hyperthyroidism, acute pulmonary embolism, recent surgery, acute myocardial infarction, etc.; (3) patients with advanced malignant tumors, liver fibrosis or pulmonary fibrosis and other serious complications; (4) Patients with a previous history of cardiac surgery or other surgical operations in the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neutrophil Extracellular Traps; | — |
Secondary
| Measure | Time frame |
|---|---|
| left atrial diameter; | — |
Countries
China
Contacts
Changzhou First People's Hospital (The Third Affiliated Hospital of Soochow University)