severe aortic valve regurgitation
Conditions
Interventions
Case series:NA
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.age >18 years old 2.severe aortic valve regurgitation 3.patients with heart failure symptoms can tolerate the intensity of exercise load (METS=2-3) 4.EF>40%
Exclusion criteria
Exclusion criteria: 1.concomitant moderate to severe aortic valve stenosis and other moderate or severe valvular disease 2.concomitant coronary heart disease 3.concomitant maligant arrhythmia(including atrial fibrillation, ventricular fibrillation and so on) 4.concomitant the history surgery ,radiotherapy or chemotherapy for maligant tumors 5.suboptimal echocardiographic images (obesity,COPD,thoracoccyllosis and so on) 6. patients disagree to join us
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative EF<50% incidence rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Left ventricular end systolic diameter;Perioperative cardiovascular adverse events (ventricular fibrillation, cardiac arrest, etc.);ICU length of stay, total length of stay;Perioperative mortality rate;brain natriuretic peptide; | — |
Countries
China
Contacts
Public ContactSong Haibo
West China Hospital of Sichuan University
Outcome results
None listed