Postoperative pain
Conditions
Interventions
Group S:Postoperative analgesia pump use: 2 µg/kg + 10 mg of tropisetron + 0.9% saline to 100 mL
Group R:Postoperative analgesia pump use: 2 µg/kg + dexketoprofen tromethamine 300 mg + tropisetron 10 mg + 0.9% saline to 100 mL
Sponsors
Hangzhou First People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. All patients were informed of the study and signed the consent form; 2. All had no contraindications to postoperative PCA and dexketoprofen use; 3. All were grade I to III according to the grading standards of the American Society of Anesthesiologists (SAS); 4. No coagulation dysfunction; 5.The subjects understand and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients who are allergic to the drugs used in this study; 2. Patients with severe disorders of important organs such as the heart, liver, and kidneys; 3. Patients with airway hyperresponsiveness; 4. Pregnant, lactating, or women who are preparing for pregnancy or whose spouses are preparing for pregnancy; 5. Patients who are currently participating in other clinical trials; 6. Patients who are considered by the researchers to be unsuitable for this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cumulative consumption of patient-controlled intravenous analgesia (PCIA) in the 48 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual analogue scale (VAS) scores immediately after awakening and at 6, 12, 24, and 48 hours after surgery;PCA single dose number;Effective compression rate of the patient's intravenous patient-controlled analgesia pump 48 hours after surgery (effective compression times/total compression times);Adverse reactions within 48 hours after surgery (respiratory depression, nausea and vomiting, itching, urinary retention, etc.); | — |
Countries
China
Contacts
Public ContactXinlei Lu
Hangzhou First People's Hospital
Outcome results
None listed