esophageal cancer
Conditions
Interventions
Non neoadjuvant therapy group:None
Sponsors
National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: ? Male and female patients aged between 18 and 80 years old; ? ASA = Level III; ? Body mass index (BMI)<40 kg/m ²; ? Expected to undergo elective esophageal cancer radical surgery for at least 3 hours.
Exclusion criteria
Exclusion criteria: ? Previous history of lung or abdominal surgery; ? Allergies or contraindications to sevoflurane, propofol, or non steroidal anti-inflammatory drugs (NSAIDs); ? Severe brain and cardiovascular dysfunction; ? Suspected or diagnosed with immune or neuromuscular diseases; ? Expected extension of mechanical ventilation time after surgery; ? Liver cirrhosis (Child B or C); ? Chronic renal failure with dialysis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence rate of neuromuscular block; | — |
Secondary
| Measure | Time frame |
|---|---|
| Differences in the dosage of rocuronium bromide during surgery;Differences in monitoring depth of intraoperative neuromuscular blockade;Residual incidence of neuromuscular blockade;CT imaging changes;Pathological changes in skeletal muscles; | — |
Countries
China
Contacts
Public ContactYan Tao
National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences
Outcome results
None listed