Chemotherapy induced nausea and vomiting
Conditions
Interventions
Case series:None
Sponsors
Beijing Chaoyang Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age = 18 years old; 2. Diagnosed as malignant tumor by pathological histology or cytology, regardless of tumor type TNM staging and previous chemotherapy status; 3. Researchers believe that chemotherapy induced nausea and vomiting should be prevented or treated with antiemetic drugs
Exclusion criteria
Exclusion criteria: 1. Individuals who have experienced symptoms such as nausea and vomiting one week prior to enrollment; 2. For 5-HT3 receptor antagonists, dexamethasone NK-1 receptor antagonists, allergic reactions to olanzapine; 3. Patients taking opioid drugs; 4. Suffering from central nervous system disorders or mental system disorders; 5. Patients with active infections or severe complications; 6. Pregnant or lactating population; 7. Other situations deemed unsuitable by researchers, such as active pulmonary tuberculosis and severe coagulation dysfunction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The proportion of subjects who complete remission within 7 days after the end of each cycle of chemotherapy treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Compliance of oral ondansetron hydrochloride tablets measured at each chemotherapy cycle;The reasons affecting the compliance of ondansetron hydrochloride tablets;After each cycle of chemotherapy, the subjects will receive a QOL questionnaire for quality of life scores;Adverse events during the treatment of 5-HT3 receptor antagonists; | — |
Countries
China
Contacts
Public ContactWenming CHEN
Beijing Chaoyang Hospital, Capital Medical University
Outcome results
None listed