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Comparison of the Efficacy of Conbercept and Aflibercept in Different Treatment Regimens for Exudative Age-related Macular Degeneration

Comparison of the Efficacy of Conbercept and Aflibercept in Different Treatment Regimens for Exudative Age-related Macular Degeneration

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400087042
Enrollment
Unknown
Registered
2024-07-18
Start date
2020-05-01
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

neovascular age-related macular degeneration

Interventions

Group 2:Group 2 were treated with a T&E regimen and received intravitreal injection of Aflibercept (2 mg)
Group 1:Group 1 were treated with a T&E regimen and received intravitreal injection of Conbercept (0.5 mg)

Sponsors

The First Affiliated Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to No maximum

Inclusion criteria

Inclusion criteria: The eligibility criteria for the study included patient's age=50 years; nAMD is confirmed through mydriatic slit lamp examination, OCT, OCTA, FFA and ICGA; No previous treatment related to nAMD (intravitreal drug injection, PDT, etc; Patients who can complete treatment follow-up for at least 12 months.

Exclusion criteria

Exclusion criteria: Patients will be excluded if they meet the following criteria. Combined with other fundus diseases, such as retinal detachment, pathological myopia, proliferative diabetic retinopathy, glaucoma, retinal vascular obstructive disease, macular membrane, macular hole, etc;Internal eye surgery or fundus laser treatment has been performed in the past, or there is a history of severe ocular trauma;Severe turbidity in the refractive medium affects the observation of fundus;Patients who failed to receive regular follow-up coordination treatment and had a follow-up period of less than 12 months and lost to follow-up.

Design outcomes

Primary

MeasureTime frame
Best-Corrected Visual Acuity(BCVA);

Secondary

MeasureTime frame
Central Retinal Thickness(CRT);injection frequency;Intraocular Pressure;

Countries

China

Contacts

Public ContactHui peng

The First Affiliated Hospital of Chongqing Medical University

pengh9@sina.com+86 130 7236 9950

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026