cancer
Conditions
Interventions
Trail group:NA
Sponsors
The First Affiliated Hospital of the Air Force Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Esophageal squamous cell carcinoma confirmed by histopathological examination; 2. The clinical stage is I-IVA, for those who cannot or refuse surgery, they will receive radical chemoradiotherapy/radiotherapy with a dose greater than 50Gy, and for those who can be operated, they will receive neoadjuvant chemoradiotherapy/radiotherapy plus surgery; 3. Before radiotherapy, chemotherapy and/or immunotherapy should not exceed 6 cycles; 4. 18-75 years old; 5. PS score=2.
Exclusion criteria
Exclusion criteria: 1. Patients with other malignant tumors; 2. Have received thoracic surgery or thoracic radiation therapy in the past; 3. Presence of esophageal fistula or has undergone esophageal stent implantation; 4. The enhanced CT image quality is too low before treatment and cannot be used; 5. The estimated survival time is less than 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Predictive performance of multiomics models for efficacy (objective response rate) of chemoradiotherapy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Predictive performance of multi-omics prediction model for local recurrence-free survival after chemoradiotherapy;Predictive performance of the multi-omics model for adverse reactions such as radiation esophagitis, radiation pneumonitis, and lymphopenia after chemoradiotherapy; | — |
Countries
China
Contacts
Public ContactLina Zhao
Department of Radiation Oncology, Xijing Hospital, Fourth Military Medical University
Outcome results
None listed