Parkinson's disease
Conditions
Interventions
propofol/etomidate:Retrospectively: No intervention, this study is an observational study
propofol/etomidate:Prospectively: No intervention, this study is an observational study
Sponsors
First Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Patients with primary Parkinson's disease undergoing bilateral subthalamic nucleus deep brain stimulation under general anesthesia with etomidate or propofol in our hospital; 2) No previous history of brain surgery; 3) Those who did not take antiparkinsonian medications before surgery; 4) Those who did not take sedative and hypnotic drugs before surgery; 5) Those who did not take antipsychotic drugs before surgery; 6) No intracranial hemorrhage during surgery.
Exclusion criteria
Exclusion criteria: 1) Those who have undergone brain surgery; 2) Preoperative use of antiparkinsonian medications; 3) Those who take sedative and hypnotic drugs before surgery; 4) Preoperative use of antipsychotic drugs; 5) Patients with intracranial hemorrhage during surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Power spectral densities;Phase-amplitude coupling (PAC); | — |
Countries
China
Contacts
Public ContactNan Jiang
First Affiliated Hospital of Sun Yat-sen University
Outcome results
None listed