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Effect of Intranasal Remimazolam besylate for Premedication on the Occurrence of Respiratory Adverse Events in Children Undergoing Tonsillectomy and Adenoidectomy:A Single-blind Randomized Controlled Study

Effect of Intranasal Remimazolam besylate for Premedication on the Occurrence of Respiratory Adverse Events in Children Undergoing Tonsillectomy and Adenoidectomy:A Single-blind Randomized Controlled Study

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400086998
Enrollment
Unknown
Registered
2024-07-17
Start date
2024-07-17
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tonsillar hypertrophy

Interventions

Sponsors

The First Hospital affiliated to NingBo University School
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 12 Years

Inclusion criteria

Inclusion criteria: ASAI-II grade 0-12 years old children undergoing elective tonsillectomy with or without adenoidectomy

Exclusion criteria

Exclusion criteria: 1: known cardiopulmonary diseases (such as uncorrected congenital heart disease, primary or secondary pulmonary hypertension, tumors or structural lung diseases) 2: neuromuscular diseases 3: body mass index (BMI) =28 4: severe URTI and anesthesiologists recommend postponement of surgery 5: allergy to remimazolam besylate 6: parents reject their children's participation in the experiment 7: other drugs that affect the respiratory system have been used in the past month

Design outcomes

Primary

MeasureTime frame
Perioperative Respiratory Adverse Events;

Secondary

MeasureTime frame
Wong-Baker Pain Scale score;Pediatric Anesthesia Emergency Delirium Scale score;Extubation time;Time spent in the postanesthesia care unit after the extubation;Vomiting rate;Bradycardia rate;Length of hospital stay;serum CRP and IL-6 :;

Countries

China

Contacts

Public ContactZhu Binbin

The First Hospital affiliated to NingBo University School

pingchi1983@126.com+86 159 5748 5723

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026