hernia operation
Conditions
Interventions
GN Group:General anesthesia + bupivacaine liposome nerve block
GB Group :General anesthesia
Sponsors
Zhongshan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
75 Years to No maximum
Inclusion criteria
Inclusion criteria: ? Elective laparoscopic hernia repair; ? Elderly patients, aged =75 years; ? ASA grade I-III, with normal preoperative sensory and motor functions; ? No history of allergy to the components of the study drugs or general anesthesia drugs, non-allergic; ? No cognitive dysfunction; ? Signed informed consent.
Exclusion criteria
Exclusion criteria: ? Refusal to sign the informed consent form; ? History of previous thoracic and abdominal surgery; ? Long history of oral pain medication or drug abuse for chronic pain; ? Severe compound trauma; ? Liver and renal insufficiency; ? History of allergy to local anesthetic drugs; ? Combined severe cardiac, hepatic, and renal insufficiency; ? Presence of uncontrolled psychiatric or neurological disorders and communication disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Perioperative opioid consumption (morphine equivalents);time to first postoperative bed movement; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS scores in resting and coughing patients;Adverse reactions associated with analgesia;Quality of night sleep on the night of surgery and on the first postoperative day;extubation time;Steward score;Ramsay score;postoperative hospitalization;perioperative complications;incidence of postoperative delirium;QoR-15 scale;frailty score; | — |
Countries
China
Contacts
Public ContactSun Minli
Zhongshan Hospital, Fudan University
Outcome results
None listed