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Efficacy and safety of ciprofol versus propofol for induction and maintenance of general anesthesia in patients undergoing thoracoscopic surgery

Efficacy and safety of ciprofol versus propofol for induction and maintenance of general anesthesia in patients undergoing thoracoscopic surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400086976
Enrollment
Unknown
Registered
2024-07-16
Start date
2023-08-22
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung tumor

Interventions

ciprofol group:Ciprofol was used for induction and maintenance of general anesthesia
propofol group:Propofol was used for induction and maintenance of general anesthesia

Sponsors

Zhejiang Cancer Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: The inclusion criteria included (1) patients undergoing thoracoscopic lobectomy or segmental resection under general anesthesia; (2) patients between the ages of 18 and 70; (3) American Society of Anesthesiologists (ASA) physical status ?-?.

Exclusion criteria

Exclusion criteria: The exclusion criteria included (1) patients with serious cardiovascular disease, including severe aortic stenosis, severe mitral stenosis, and significant arrhythmias; (2) patients with significant hepatic or renal insufficiency; (3) patients who have been taking sedative agents or antidepressants for a long time; (4) patients who had underwent surgery under general anesthesia within 4 weeks of the perioperative period. (5) women who were pregnant or planning to become pregnant within 1 month; (6) patients refusing to participate in the study.

Design outcomes

Primary

MeasureTime frame
Success rate of induction and maintenance of general anesthesia ;

Secondary

MeasureTime frame
Incidence of adverse reactions during general anesthesia;Induction success time ; The time to eyelash reflex disappearance;The moment when BIS value dropped to 60;Incidence of injection pain;Duration of surgery;Duration of anesthesia;Respiratory recovery time ;Wakefulness time;Medication use;The duration until discharge from the post-anesthesia care unit;

Countries

China

Contacts

Public ContactWangying

Zhejiang Cancer Hospital

caitlinwy@163.com+86 178 1673 0661

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026