benign prostatic hyperplasia
Conditions
Interventions
test group:Perform ejaculatory-hood sparing resectin of prostate, tissues approximately 1 cm proximal to the seminal caruncle are preserved, and the distal prostatic hyperplastic tissue as well as the
control group:standard transurethral resectin of prostate, the prostatic hyperplastic tissue distal to seminal caruncle as well as the bladder neck are removed.
Sponsors
The Third Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
Male
Age
45 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. 45-75 year-old male, clinically diagnosed with BPH, and prostate volume =40 ml. 2.BPH patients with moderate-to-severe LUTS that have significantly affected their quality of life, especially those who have failed or refused or are unable to accept drug therapy. 3.BPH with complications: recurrent urinary retention; recurrent urinary tract infections; bladder stones or diverticula; recurrent hematuria; secondary upper urinary tract hydronephrosis (with or without renal impairment) . 4. BPH patients who have a combination of inguinal hernia, severe hemorrhoids, or prolapse, difficult to achieve therapeutic benefit without relief of lower urinary tract obstruction. 5.Patients who have regular sexual life (at least once a month) and normal ejaculatory function. 6.Agree to participate in this clinical study and sign the informed consent form. (2), (3), (4) can meet one of them.
Exclusion criteria
Exclusion criteria: 1. A history of previous prostate surgery or lower urinary tract surgery. 2.Suspicion of prostate cancer requiring prostate puncture. 3.Patients diagnosed with prostate cancer. 5.Those who already have urinary incontinence, retrograde ejaculation or no longer have a regular sexual life before the operation. 5.Presence of weak or overactive contraction of the urethral muscle. 6.Those with severe cardiovascular or cerebrovascular disease, psychiatric disorders, or those assessed by the clinician to be unsuitable for enrollment in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Retrograde ejaculation rate;Evaluation of prostate symptoms;Evaluation of de-obstruction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of prostate symptoms;Evaluation of ejaculatory function; | — |
Countries
China
Contacts
Public ContactYunLuo
The Third Affiliated Hospital of Sun Yat-sen University
Outcome results
None listed