anxiety
Conditions
Interventions
Group A (Anxiety Self Rating Scale score less than 50 points,depth of sedation observed):Upward and Downward Adjustment of remimazolam-Inducing Drug Doses by the Biased Coin Sequencing Method
Group B ((Anxiety Self Rating Scale score greater than or equal to 50, observe the depth of sedation):Upward and Downward Adjustment of remimazolam-Inducing Drug Doses by the Biased Coin Sequencing Me
Group C(Anxiety Self Rating Scale score less than 50 points,Observe the somatokinetic reaction):Upward and Downward Adjustment of remimazolam-Inducing Drug Doses by the Biased Coin Sequencing Method
Grou D(Anxiety Self Rating Scale score greater than or equal to 50,Observe the somatokinetic reaction):Upward and Downward Adjustment of remimazolam-Inducing Drug Doses by the Biased Coin Sequencing M
Sponsors
Shaoxing People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) ASA Grade I to II agrees to participate in this experiment and signs a written informed consent; (2) Age 18-60 years; (3)Body mass index (BMI) : 18.5 ~ 28kg/m^2; (4) Patients undergoing elective painless gastroscopy.
Exclusion criteria
Exclusion criteria: 1) Patients with mental illness, long-term use of psychotropic drugs and alcohol or drug abuse; (2) Patients with neurological diseases such as dementia and Parkinson's disease, and previous history of cerebrovascular accidents or craniocerebral surgery; (3) Patients with severe visual or hearing impairment and difficulties in language communication; (4) Patients with obvious liver and kidney dysfunction and serious cardiopulmonary disease; (5) Allergic or contraindicated to benzodiazepines, opioids and drug components.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the median effective effect-concentration;the 90% effective effect-concentration;95% confidence interval; | — |
Countries
China
Contacts
Public ContactHu Shuangyan
Shaoxing People's Hospital
Outcome results
None listed