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Clinical efficacy of Huang He decoction on allergic rhinitis with lung spleen qi deficiency type and its influence on nasal immune factors

Clinical efficacy of Huang He decoction on allergic rhinitis with lung spleen qi deficiency type and its influence on nasal immune factors

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400086920
Enrollment
Unknown
Registered
2024-07-15
Start date
2024-07-18
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Allergic rhinitis

Interventions

control group:Taking Loratadine orally
experimental group:Taking Huanghe decoction and Loratadine orally

Sponsors

The Seventh People's Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Traditional Chinese Medicine (TCM) Syndrome Standards: TCM syndrome types are determined by two TCM doctors to be lung spleen qi deficiency syndrome. Symptoms are heavy nasal congestion, thin or sticky white mucus, dripping down, dull sense of smell, swelling, pale or dull color or polypoid changes in both inferior turbinates. The whole body is accompanied by dizziness and heaviness, fatigue and shortness of breath, fatigue in all limbs, and poor appetite and diarrhea. The tongue is light and chubby, with tooth marks on the edges, white coating, and weak pulse. 2. Western medicine symptom criteria: Two or more symptoms such as nasal congestion, watery nasal discharge, nasal itching, and sneezing, lasting or accumulating for more than 1 hour per day, may be accompanied by eye symptoms, and the symptoms are perennial. Common allergens include indoor perennial inhaled allergens such as dust mites, cockroaches, and animal dander. 3. Signs: Common nasal mucosal pallor, edema, and watery nasal discharge. 4. Allergen testing: At least one allergen serum specific antibody IgE is positive. 5. Age between 18 and 65 years old. 6. No use of anti allergic drugs in the past three months. 7. Sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Those with obvious concurrent or combined certificates 2. Accompanied by severe or uncontrolled asthma. 3. Accompanied by serious systemic diseases including malignant tumors, hematological disorders, etc. 4. Immunodeficiency diseases. 5. Female patients during lactation and pregnancy. 6. Patients with mental illness. 7. Those who cannot take medication on time due to other reasons. 8. Patients who participate in other clinical trials simultaneously.

Design outcomes

Primary

MeasureTime frame
Symptom score;

Secondary

MeasureTime frame
Traditional Chinese Medicine Syndrome Score;RQLQ survey questionnaire;Nasal secretion IgE;Nasal secretion IL-4;Nasal secretion IL-5;Nasal secretion INF - ?;Eosinophil count in nasal secretions;

Countries

CHINA

Contacts

Public ContactFan yong jiang

The Seventh People's Hospital Affiliated to Shanghai University of Traditional Chinese Medicine

47390242@qq.com+86 199 2167 4630

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026