A System for Localizing Epileptogenic Focus in Patients with Cortical Developmental Malformations Based on Artificial Intelligence and Machine Learning

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2400086917

Enrollment

Unknown

Registered

2024-07-15

Start date

2024-07-15

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malformation of cortical development

Interventions

Observation group:None

Eligibility

Sex/Gender

All

Age

1 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1.Diagnosed with MCD according to the diagnostic criteria of ILAE; 2.Experienced intractable epilepsy and seizures occurring at least twice per month on average during the six months prior to surgery; 3.Underwent comprehensive preoperative evaluations and epilepsy surgery at our comprehensive epilepsy center; 4.Completed 18F-FDG PET examination more than 48h since the last seizure; 5.Completed at least 1-year follow-up

Exclusion criteria

Exclusion criteria: 1.History of other specific neurological abnormalities; 2.Contraindications for imaging examinations; 3.Dropouts or Lost follow-up

Design outcomes

Primary

Measure	Time frame
18F FDG PET;Computed Tomography (CT);Magnetic Resonance Imaging (MRI);AUC;Accuracy;	—

Countries

China

Contacts

Public ContactZhongke Wang

Armed Police Hospital of Chongqing

wangzhongke2020@163.com+86 188 8392 2006

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026