colorectal cancer.
Conditions
Interventions
combined with chemotherapy for at least 4 cycles.
chemotherapy alone group.:Use FOLFOX or CapeOx first-line chemotherapy regimen, with at least 4 cycles of chemotherapy.
Spleen-invigorating and detoxifying method combined with chemotherapy group.:On the basis of chemotherapy, the Yiqi, Jianpi and Anti-Cancer Recipe (composed of: Radix Pseudostellariae, Poria Cocos, At
for severe nausea and vomiting, add Pinellia ternata, tangerine peel, and Inula
for qi stagnation and abdominal pain, add Corydalis chinensis, white peony root, costus, and Citrus aurantium
for those with mid-coke deficiency and cold abdominal pain, Add dried ginger, Evodia, and cinnamon
for patients with palpitations and insomnia, add jujube kernels, Polygala, and Albizia Julibrissin bark
for patients with anorexia, add hawthorn, Divine Comedy, malt, etc., three times a day, 100ml each time
Sponsors
Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Clinical observation of traditional Chinese medicine syndrome types in patients undergoing postoperative chemotherapy for colorectal cancer: ? Patients diagnosed pathologically as stage II-IV colorectal cancer; ? Patients who have not undergone chemotherapy and no clear recurrence and metastasis at the time of enrollment; ? Ages =18 and =80 years old Adults within; ?KPS score =70 points (KPS score is the functional status scoring standard, the higher the score, the better the health status, and the more able to tolerate the side effects of treatment on the body); ?The patients are all post-surgery cases. To clarify the effect of spleen-strengthening and detoxification method on adverse reactions of postoperative chemotherapy for colorectal cancer: western medicine inclusion criteria: ? Patients with pathologically diagnosed high-risk stage II-III colorectal cancer; ? No chemotherapy and no clear recurrence and metastasis at the time of enrollment; ? Adults aged =18 and =80 years old; ?KPS score =70 points; ?The patients are all post-operative cases. Inclusion criteria for traditional Chinese medicine: With reference to the "Clinical Guiding Principles for New Traditional Chinese Medicines" and under the guidance of experts and professors from our hospital's research team, the dialectical criteria for spleen deficiency syndrome were formulated: main symptoms: sallow complexion, fatigue, lack of appetite, abdominal pain; concurrent symptoms : Nausea and vomiting, epigastric and intestinal borborygmus, edema, weak defecation, loose stools, weight loss; Tongue and pulse: Pale white or red tongue, tooth marks on the fat side, thin white or yellow fur, thin or heavy pulse.
Exclusion criteria
Exclusion criteria: ? Those who have undergone chemotherapy, radiotherapy, targeted therapy, immunotherapy and other treatments; ? Those with serious underlying diseases; ? Those with obvious liver, kidney and other functional impairments, or mental patients, pregnant or lactating women; ? Allergic constitution or resistance to multiple drugs Allergic persons; ? Subjects who the researcher believes have factors that are not suitable for participating in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tongue;pulse;Clinical symptoms.;TCM syndrome types;Spleen deficiency symptom score.;KPS rating;Laboratory indicators (blood routine, liver and kidney function, tumor markers, immune function).;Piper fatigue score.;Toxicity and side effects indicators (blood system: white blood cells, red blood cells, hemoglobin, neutrophils, gastrointestinal reactions: oral ulcers, nausea and vomiting).; | — |
Countries
China
Contacts
Public ContactLi Wusheng
Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University.
Outcome results
None listed