Obesity-diarrhea syndrome
Conditions
Interventions
experimental group:mesalazine
control group:placebo
Sponsors
Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Age range from 18 to 65 years old; 2) Long term chronic diarrhea: meets the diagnostic criteria for chronic diarrhea; 3) Obesity: BMI greater than 28kg/m2; 4) Routine examinations of the patient, such as blood, urine, stool, biochemistry, abdominal CT, gastrointestinal endoscopy, etc., did not show any organic lesions; (5) Sign an informed consent form.
Exclusion criteria
Exclusion criteria: (1) Suffering from diseases such as intestinal infections, inflammatory bowel disease, irritable bowel syndrome, and malabsorption syndrome that can clearly cause diarrhea; (2) Patients who have undergone surgical procedures such as cholecystectomy and gastrointestinal resection; (3) Suffering from serious cardiovascular diseases, liver and kidney dysfunction, and other diseases, with contraindications for anesthesia; (4) Pregnant or breastfeeding patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fecal frequency and Bristol fecal trait typing; | — |
Secondary
| Measure | Time frame |
|---|---|
| Related indicators such as blood and tissue inflammatory factors; | — |
Countries
China
Contacts
Public ContactEnqiang Linghu
Chinese PLA General Hospital
Outcome results
None listed