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Effect of prophylactic intravenous pumping of norepinephrine on maternal hypotension after combined lumbar and rigid anaesthesia for caesarean section

Effect of prophylactic intravenous pumping of norepinephrine on maternal hypotension after combined lumbar and rigid anaesthesia for caesarean section

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400086873
Enrollment
Unknown
Registered
2024-07-12
Start date
2024-08-01
Completion date
Unknown
Last updated
2024-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perioperative hypotension

Interventions

Case series :Intravenous pumping of different doses of norepinephrine

Sponsors

The Third People's Hospital of Bengbu
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: (1) full-term women =37 weeks of gestation; (2) aged between 18 and 40 years; (3) intending to undergo elective caesarean section under combined lumbar and rigid anaesthesia; and (4) women voluntarily participating in the trial and signing an informed consent form.

Exclusion criteria

Exclusion criteria: (1) women with severe cardiovascular or cerebrovascular disease; (2) women with gestational hypertension, supine hypotension syndrome, or diabetes mellitus; (3) women with known fetal anomalies; (4) women with an allergy or intolerance to norepinephrine; (5) women with recent use of monoamine oxidase inhibitors; (6) women with a body mass index of more than 35 kg/m²; (7) women whose height is more than 180 cm or less than 150 cm; (8) women whose baseline systolic blood pressure is less than 100 mmHg; (9) women with an American Society of Anesthesiologists (ASA) classification of grade III or greater; (10) women with any other contraindication to intrathecal anesthesia. Women with a baseline systolic blood pressure of less than 100 mmHg; women with an American Society of Anaesthesiologists (ASA) classification of grade III or higher; and women with any other contraindication to intrathecal anaesthesia.

Design outcomes

Primary

MeasureTime frame
Effective dose of pumped norepinephrine;blood pressure;

Secondary

MeasureTime frame
Neonatal Apgar score;Neonatal umbilical artery blood gas;Nausea;Vomiting;heart rate;

Countries

China

Contacts

Public ContactChengfei Xu

The Third People's Hospital of Bengbu

bbxcfpain@163.com+86 152 5509 8850

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026