Hypertension
Conditions
Interventions
Control Group:Lifestyle Intervention
Qianyang Yuyin granule placebo 20G/time, taking with warm water in the morning and evening
Treatment Group:Life style intervention
Qianyang Yuyin granule 20G/time, taking with warm water in the morning and evening
Sponsors
Jiangsu Provincial Hospital of traditional Chinese medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) age 18-65 years, gender is not limited, 2) diagnostic criteria of normal high blood pressure: without the use of antihypertensive drugs, the mean sitting systolic blood pressure (SBP) and/or diastolic blood pressure (DBP) of brachial artery were 120-139 mmhg and 80-89 mmhg, respectively The mean sitting systolic blood pressure (SBP) of brachial artery was 115-135mmHg, and/or mean sitting diastolic blood pressure (DBP) of 75-85 mmhg) , 3) were able to perform mild to moderate exercise, 4) voluntarily participated in the trial and signed an informed consent form
Exclusion criteria
Exclusion criteria: 1) secondary high normal blood pressure caused by other causes such as primary aldosteronism, hypercholesterolemia, or severe dysfunction or malignant diseases of important organs such as heart, liver, kidney, hematopoietic system, or metabolic diseases such as diabetes, hyperlipidemia, and Hyperuricemia; 2) patients who were treated with antihypertensive drugs 2 weeks before admission; 3) the use of antibiotics, probiotics, microbial preparations, Proton-pump inhibitor, various types of proprietary Chinese medicines (including but not limited to Xiaochaihu decoction, Yupingfeng powder, Sijunzi decoction, etc.) , traditional Chinese medicine decoction, Chinese medicine instead of tea drink, etc. 4) history of gastrointestinal tract disease (including diarrhea and constipation in the last 1 month) , history of digestive tract operation ,5)and other relevant medical history affecting intestinal flora ,6) excluding pregnant and lactating women; 7)excluding allergic constitution or known allergy to drug ingredients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24h ambulatory blood pressure;Office blood pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Lifestyle scale integral; | — |
Countries
China
Contacts
Public ContactFang Zhuyuan
First Nanjing University of Chinese Medicine Medical College (Jiangsu Provincial Hospital of traditional Chinese medicine)
Outcome results
None listed