overweight/Obesit
Conditions
Interventions
Overweight/obese energy restriction group:Low calorie intake intervention
Overweight/obese in traditional Chinese medicine exercise group combined with energy restriction group (Bigu group):Traditional exercise combined with no energy intake intervention
Overweight/obese in traditional Chinese medicine exercise group combined with low energy restriction group:Traditional exercise combined with low energy intake intervention
Sponsors
Ningxia Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. People who meet the diagnostic criteria for overweight/obesity or central obesity; 2. Age 18-40 years old; 3. Clear consciousness, no dementia, memory disorders and other consciousness problems; 4. Normal movement, no neuromuscular body diseases; 5. There is sufficient time for intervention; 6. Patients voluntarily participate in the study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Have taken drugs that affect weight within the past 1 month or have undergone weight-loss surgery within 1 year; 2.Subjects who lost more than 5Kg in the past two months due to various causes; 3. Patients with secondary obesity who gain weight due to drugs, endocrine diseases or other diseases; 4. Combined with severe liver and kidney dysfunction or other serious primary diseases; 5. Obese patients with chronic diseases such as hypertension and hyperlipidemia; 6. Patients with various other chronic diseases who need to take medication for a long time and affect the test results; 7. Patients with gastrointestinal diseases, and those who used antibiotics, prebiotics and other drugs affecting intestinal flora 1 month before the test;
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Intestinal mucosal barrier function (DAO and ET levels);Body weight, BMI, and body composition indicators;Fasting blood glucose , blood lipid profile, insulin, and glycated hemoglobin; | — |
Primary
| Measure | Time frame |
|---|---|
| Changes in gut microbiota structure and function;Fecal metabolomic changes; | — |
Countries
China
Contacts
Public ContactGuo Jianhong
Ningxia Medical University
Outcome results
None listed