ED95 of unilateral spinal anesthesia with light specific gravity ropivacaine in elderly patients undergoing arthroplasty

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400086829

Enrollment

Unknown

Registered

2024-07-11

Start date

2024-07-15

Completion date

Unknown

Last updated

2024-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diseases of the Hip and Knee

Interventions

Sequential group 1:Different doses of light gravity ropivacaine

Sequential group 2:Time in side-lying position

Eligibility

Sex/Gender

All

Age

65 Years to No maximum

Inclusion criteria

Inclusion criteria: ? ASA grade I to III; ? Patients undergoing elective hip and knee arthroplasty; ? age = 65 years old, gender is not limited; ? BMI 18.5-23.9kg/m2; ? no contraindications to intralesional anesthesia; ? those who signed the informed consent form.

Exclusion criteria

Exclusion criteria: ? previous history of spinal surgery, spinal deformity; ? ropivacaine and other drugs allergy; ? intrathecal anesthesia contraindications; ? heart, liver and kidney insufficiency; ? lower limb motor, hearing dysfunction

Design outcomes

Primary

Measure	Time frame
ED50 and ED95 of unilateral spinal anesthesia with light gravity ropivacaine;ED50 and ED95 for unilateral spinal plane immobilization time;	—

Secondary

Measure	Time frame
plane of anesthesia;postoperative complication;hemodynamics;Modified Bromage score of the affected limb;Modified Bromage score for the healthy limb;Onset of anesthesia;Duration of anesthesia;	—

Countries

China

Contacts

Public Contactfangjun-wang

Affiliated Hospital of Sichuan Bei Medical College

296008938@qq.com+86 134 5825 3172

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026