Parkinson's disease
Conditions
Interventions
real treatment group:Induction and maintenance of anesthesia with remimazolam
sham treatment group:Induction and maintenance of anesthesia with remimazolam
Sponsors
Xiangya Hospital Central South University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) ASA ? - ? level; 2) patients with PD requiring elective bilateral STN-DBS; 3) voluntary and signed informed consent
Exclusion criteria
Exclusion criteria: ? previous neurosurgery; ? combined with psychiatric systemic diseases (such as schizophrenia, mania, depression, bipolar disorder, Alzheimer's disease, etc.; ? any severe or uncontrolled systemic illness that may significantly affect the patient's risk/benefit balance; ? known or suspected allergy to drugs or components related to the study; ? The researchers determine doesn't fit in other circumstances.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Root mean square values of local field potential;power spectrum density;spikes ;The average length of the STN in the trajectory;Bispectral index; | — |
Secondary
| Measure | Time frame |
|---|---|
| UPDRS ? improvement rate; | — |
Countries
China
Contacts
Public ContactTao Zhong
Xiangya Hospital Central South University
Outcome results
None listed