Dysphagia after stroke
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patient inclusion criteria: ? Stroke patients who met the diagnostic criteria of "Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke 2018" or "Chinese Guidelines for the Diagnosis and Treatment of Cerebral Hemorrhage (2014)" issued in 2018 were confirmed by head CT or MRI imaging scans; ? The course of disease =2 weeks and =12 months, the condition was stable; ? Age 18-85; ? The patient has swallowing dysfunction; ? mini-mental state examination (MMSE) =17 points; ? Patients have clear consciousness, stable vital signs, and can cooperate with training; ?Promise to comply with research procedures and cooperate with the whole process of research; ? Commit to observe lifestyle considerations during the study; Willing to sign the informed consent for this study. Normal inclusion criteria: ? Age 18-85; ? The subject has good swallowing condition, no history of swallowing disorder, no other history related to swallowing organ function, and can complete normal swallowing; ?The subject has no visual or hearing impairment (or normal visual or hearing correction), unconscious impairment and cognitive impairment, and can understand Mandarin and the instructions given and the requirements requiring attention; ? No ADHD, neurological or psychiatric disorders (autism, claustrophobia); ? The subject undertakes to abide by the research procedures and cooperate with the whole process of research; ? Commitment to observe lifestyle considerations during the study; ? Willing to sign the informed consent for this study.
Exclusion criteria
Exclusion criteria: ? The patient has a history of swallowing dysfunction due to other causes (Parkinson's disease, dementia, motor neurone disease, etc.); ? accompanied by consciousness disorders or cognitive dysfunction, mental disorders and mixed aphasia impact assessment and treatment; ?The subjects have serious dysfunction of liver, kidney, heart and other important organs; ? Built-in pacemaker; ? barium sulfate allergy; ? People with severe visual and hearing impairments; ?Pregnant or lactating women; ? The absence of skull; ?Any condition which, in the opinion of the investigator, is likely to harm the subject or cause the subject to be unable to meet or perform the study requirements.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Activation and lateralization index;Functional connection strength;Brain network analysis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Event-Related Potential;Simplified Nutritional Appetite Questionnaire;visual analogue scale;quantitative analysis of video fluoroscopic images for swallowing;Rosenbek penetration-aspiration scale;Standardized Swallowing Assessment;Simplified Nutritional Appetite Questionnaire; | — |
Countries
China
Contacts
Department of Rehabilitation Medicine, the Second Affiliated Hospital of Xi 'an Jiaotong University