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Optimization of propofol remifentanil compound anesthesia injection method in painless gastrointestinal endoscopy

Optimization of propofol remifentanil compound anesthesia injection method in painless gastrointestinal endoscopy - Optimization injection method

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400086791
Enrollment
Unknown
Registered
2024-07-11
Start date
2024-07-19
Completion date
Unknown
Last updated
2024-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Induction period half dose rapid injection group (Group A):Group A patients were intravenously injected with a mixture of propofol and remifentanil at a dose of 1/2 of the theoretical induction dose,
Quarter dose rapid injection group (Group B):Group B patients were intravenously injected with a mixture of propofol remifentanil at a dose of 1/4 of the theoretical induction dose, with a duration of
Constant speed pump injection group (Group C):Group C patients were intravenously injected with a mixture of propofol and remifentanil, and all theoretical induced doses were uniformly pumped at a spe

Sponsors

The First Affiliated Hospital of Nanjing Medical University (Jiangsu Provincial People's Hospital)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients aged = 18 years but<80 years, who underwent both gastroscopy and colonoscopy, and ASA grades I-III voluntarily joined.

Exclusion criteria

Exclusion criteria: ? BMI>30kg/m2 ? Breathing air SpO2 < 95% ? Poor blood pressure control (systolic blood pressure = 180mmHg or diastolic blood pressure = 110mmHg) ? Ventricular rate<50 beats/min or malignant arrhythmia (ventricular fibrillation, ventricular tachycardia, preexcitation syndrome with atrial fibrillation, third degree atrioventricular block) ? Communication barriers ? History of drug allergies or allergies to eggs or soybeans

Design outcomes

Primary

MeasureTime frame
The incidence of body movements (mild limb movements, hiccups, coughing, restlessness);

Secondary

MeasureTime frame
The incidence of respiratory related adverse events (SpO230% basal blood pressure, heart rate<50bmp);Induction duration;Duration of gastroscopy examination;Awakening time;Dosage of anesthesia;Dosage of vasoactive drugs used;Vital signs;

Countries

China

Contacts

Public ContactGe Jingwu

Jiangsu Provincial People's Hospital

jsgjw2009@163.com+86 139 1449 8967

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026